ThermoReLeaf

At ThermoReLeaf we address the problem of crop yield losses due to heat exposure

, a global threat to food security that has worsened in recent years due to climate change.

The Challenge

It is estimated that each degree-Celsius increase in global mean temperature reduces global yields of wheat by 6.0%, rice by 3.2%, maize by 7.4%, and soybean by 3.1%.

This represents a total global average loss of $42.4 billion per year.

Our Solution

ThermoReLeaf develops biological solutions that protect crops from extreme heat.

Most existing approaches act biologically too late.

Irreversible heat damage begins within plant cells long before visible symptoms appear. ThermoReLEAF targets the cellular mechanisms that trigger heat-induced cell death, helping crops maintain productivity under extreme temperatures.

Built for real-world agriculture

Works under extreme heat (>40°C)
Plug-and-play (seed & foliar)

Current technologies are not specifically developed to cope with severe heat

We are able to precisely disrupt the cell death mechanism triggered in response to heat without affecting plant growth or development

Our technologies are applicable across species with no changes to existing bioinput production or farming practices.

Impact

By providing heat-resistant crops, ThermoReLeaf is committed to restore crop profitability and to reduce the social impact of climate change.

Through technological innovation, ThermoReLeaf promotes economic growth, higher levels of productivity and sustainable agricultural practices.

Our Team

ThermoReLeaf is a biotechnology startup founded in 2024.

We based our startup in years of research and strong science.

Gabriela C. Pagnussat
CEO

PhD in Life Sciences, Molecular and Cell Biologist. UCDavis, HHMI IECS.

CONICET Researcher UNMDP.

Ayelén M. Distéfano
CSO

PhD in Life Sciences, Plant Physiologist.

CONICET Researcher UNMDP.

Diego F. Fiol
CTO

PhD in Life Sciences, Molecular biologist, Bioinformatic Leadership & management UCDavis.

CONICET Researcher UNMDP.

At ThermoReLeaf we address the problem of crop yield losses due to heat exposure

ThermoReLeaf develops biological solutions that protect crops from extreme heat.

Most existing approaches act biologically too late. Irreversible heat damage begins within plant cells long before visible symptoms appear. ThermoReLEAF targets the cellular mechanisms that trigger heat-induced cell death, helping crops maintain productivity under extreme temperatures.

Most existing approaches act biologically too late.

Irreversible heat damage begins within plant cells long before visible symptoms appear. ThermoReLEAF targets the cellular mechanisms that trigger heat-induced cell death, helping crops maintain productivity under extreme temperatures.